Lab Animal Pathology Kurs
- Wird im Rahmen des PhD-Programms “ Medical Life Science and Technology” am Graduate Center of Medicine and Health (School of Medicine and Health, TUM) angeboten.
- Nächster Termin: 07.-11.04.2025
- Anmeldung an cep(at)mh.tum.de
- Individuelle Termine für größere externe Gruppen auf Anfrage möglich
Kursbeschreibung:
Description and accurate diagnosis of pathologic lesions in laboratory animals modeling human diseases is of essential importance for the success of modern biomedical and translational research.
The laboratory animal and comparative pathology course will provide foundational knowledge of:
- general pathology + histology
- technical aspects of histological tissue work-up (sampling, trimming, and fixation)
- mouse necropsy
- basics of histochemistry and immunohistochemistry
- normal gross anatomy and histology and their species- and strain-specific differences
- background pathology in laboratory animals
- gross and microscopic patterns of spontaneous and infectious diseases in laboratory animals (focused on mice and rats)
- comparative tumor and infectious pathology and animal models of human diseases
- pathological background of selected animal welfare aspects
- applied macroscopic and histologic pathological techniques
- (semi-)quantitative evaluation and scoring systems
After completing the course, PhD students should be able to:
- decide and perform adequate tissue asseverations and fixation after animal dissection
- prepare histological slides with standard staining and know about selected special stains and immunohistochemical methods
- differentiate background lesions from individual/experimental or model-based alterations
- macro- and microscopically describe, sample and diagnose inflammatory and neoplastic lesions in laboratory animals